B4750 - Does physical activity moderate the relationship between genetic liability to depression and severity of depressive symptoms - 25/11/2024

B number: 
B4750
Principal applicant name: 
Robyn Wootton | School of Psychological Science, University of Bristol
Co-applicants: 
Farzana Ali
Title of project: 
Does physical activity moderate the relationship between genetic liability to depression and severity of depressive symptoms?
Proposal summary: 

Individuals with a higher genetic propensity for depression are more likely to experience later depression symptoms. Evidence suggests moderate effects of exercise on improving symptoms of depression and anxiety. In this project, we explore whether the effects of exercise on depression symptoms differ depending on the genetic liability of the individual.

Impact of research: 
Better understand how exercise can differentially affect mental health outcomes and better tailor exercise interventions towards who they will be most effective for.
Date proposal received: 
Friday, 22 November, 2024
Date proposal approved: 
Monday, 25 November, 2024
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Mental health, Statistical methods, Genetic epidemiology