B4733 - Exercise in adolescence as a protective factor against negative neurodevelopmental effects of bullying - 05/11/2024

B number: 
B4733
Principal applicant name: 
Cecilia Flores | McGill University (Canada)
Co-applicants: 
Nathaniel Roy, Fatme
Title of project: 
Exercise in adolescence as a protective factor against negative neurodevelopmental effects of bullying
Proposal summary: 

Healthy socialization plays a crucial role in adolescent maturation. Social stress is known to hamper proper development of the prefrontal cortex and its dopamine dynamics. The dopamine system is tightly linked to brain processes underlying impulse control, social behavior and cognition. Social adversity commonly occurs during adolescence. We can aim to reduce bullying, but this stressor cannot be avoided entirely, so it is necessary that we understand how to protect against its long-term negative effects on the brain. There is some evidence that physical exercise can prevent, reduce, or reverse negative effects of adverse experiences on brain function and behavior.

Impact of research: 
This research will eventually inform if and how physical exercise should be considered and implemented as an intervention to protect against detrimental effects of social adversity in adolescence.
Date proposal received: 
Friday, 1 November, 2024
Date proposal approved: 
Tuesday, 5 November, 2024
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Mental health, Statistical methods, BMI, Cohort studies - attrition, bias, participant engagement, ethics, Psychology - personality, Physical - activity, fitness, function, Sex differences, Statistical methods, Childhood - childcare, childhood adversity, Cognition - cognitive function, Communication (including non-verbal), Development, Epigenetics, Hormones - cortisol, IGF, thyroid, Metabolic - metabolism, Neurology