B4697 - Understanding childhood adversity and co-occurring overweight and internalizing symptoms using life course and genetically-infor - 23/09/2024

B number: 
B4697
Principal applicant name: 
Laura Howe | MRC IEU, PHS, Bristol Medical School (United Kingdom)
Co-applicants: 
Ka Kei Sum, Jon Heron, Annie Herbert
Title of project: 
Understanding childhood adversity and co-occurring overweight and internalizing symptoms using life course and genetically-infor
Proposal summary: 

Adverse childhood experiences (ACEs) are associated with multiple negative health behaviors and consequences including both physical and mental health conditions in adulthood. Previous studies have commonly examined the impact of ACEs on a single outcome. However, recent evidence shows that exposure to ACEs may also increase the risk of multimorbidity such as overweight or obesity in combination with mental health conditions. This project will explore this, and the mechanisms through which the co-occurrence of overweight/obesity and mental health problems might arise.

Impact of research: 
Improved understanding of potential intervention targets to mitigate the effects of ACEs on health
Date proposal received: 
Thursday, 19 September, 2024
Date proposal approved: 
Monday, 23 September, 2024
Keywords: 
Epidemiology, Mental health, Obesity, BMI, Childhood - childcare, childhood adversity