Child maltreatment including traumatic experiences such as physical or sexual abuse is a consistent risk factor for depressive disorders. Depression often results from a combination of environmental, biological and psychological factors. Factors that explain this association between childhood trauma and depression are still being studied. Genetic factors could be a bridge between environmental stressors and the pathophysiology of depression. Research has already shown that parenting practices could be a protective factor for depression development; however, research is needed to explore the interaction between epigenetics and parenting in predicting depression symptoms in children. This study seeks to address these gaps in the literature.