B4597 - Maternal perinatal depressive symptoms and offspring hypomanic symptoms at 22 years a prospective UK birth cohort study - 29/04/2024
B number:
B4597
Principal applicant name:
Gemma Lewis | University College London
Co-applicants:
Dr Ramya Srinivasan, Prof Glyn Lewis, Phoebe Duffett
Title of project:
Maternal perinatal depressive symptoms and offspring hypomanic symptoms at 22 years – a prospective UK birth cohort study
Proposal summary:
Hypomania is a state of unusually energetic, high or irritable mood which lasts at least 4 days in a row. Hypomania can accompany depressive episodes as part of the course of bipolar disorder. There is evidence that suggests that maternal depression in pregnancy and the postnatal period is associated with various mental health outcomes in their children, including depression and psychotic symptoms as teenagers. However, little is known about how maternal depression in pregnancy and the postnatal period may relate to hypomania. This project will investigate whether maternal depression in pregnancy and the postnatal period is linked to their children’s hypomania when they are young adults.
Impact of research:
This study will add to the growing body of literature which shows that perinatal experiences can have long-term influences on offspring mental health into adolescence and young adulthood. Understanding the potential effects of perinatal experiences on longer term offspring mental health is important in terms of population health, prevention and early intervention.
Date proposal received:
Thursday, 18 April, 2024
Date proposal approved:
Tuesday, 23 April, 2024
Keywords:
Epidemiology, Mental health, Statistical methods, Cohort studies - attrition, bias, participant engagement, ethics