Metabolomics, defined as the measurement and study of circulating small molecules that are the substrates and products of cellular metabolism, is increasingly used by epidemiologists to provide a functional read-out of bulk cellular activity and a proxy to individual current health. This approach also provides insight into biological pathways linking exposures and disease. Nightingale Health’s nuclear magnetic resonance (NMR) spectroscopy-based metabolomic research service enables reproducible and cost-effective measurement of lipids, inflammation, dietary intake and insulin sensitivity (https://research.nightingalehealth.com/). The platform enables absolute quantification of close to 200 metabolites and includes 39 clinically validated biomarkers. This platform has already been used to generate metabolomics data from samples collected during the G1 clinics at age 7, 15, 17 and 24 years. We propose to generate NMR data from samples collected during the age 30 clinic. This work will enable us to extend the longitudinal dataset into the latter part of early adulthood. In epidemiology, this is a traditionally understudied part of the life course but one which we believe may offer important insights into the development of disease later in adulthood.