B4498 - Cognitive inflammatory and brain trajectories in individuals with psychotic experiences2 - 18/12/2023

B number: 
B4498
Principal applicant name: 
Kate Merritt | University College London (United Kingdom)
Co-applicants: 
Lina Robinet
Title of project: 
Cognitive, inflammatory and brain trajectories in individuals with psychotic experiences2
Proposal summary: 

Impairments in cognitive performance are present before psychosis onset, however the relationship between cognitive trajectories and brain development is unknown. In this project we will investigate whether altered brain development is associated with impaired cognitive performance, and whether this is more common in those with psychotic experiences. Inflammation is thought to play a role in the development of psychosis. This project will examine whether inflammatory markers are higher in those with psychotic experiences, and whether they are associated with brain changes. We do not need additional data as we will be using data from B3035.

Impact of research: 
Journal publication
Date proposal received: 
Monday, 18 December, 2023
Date proposal approved: 
Monday, 18 December, 2023
Keywords: 
Neurology, Mental health, Medical imaging, Biological samples -e.g. blood, cell lines, saliva, etc.