B4495 - Multi-omics analysis of nursery thermometer study - 18/12/2023

B number: 
B4495
Principal applicant name: 
Neil Goulding | Centre for Academic Child Health, Population Health Sciences, Bristol Medical School, University of Bristol (United Kingdom)
Co-applicants: 
Dr Matthew Suderman, Professor Jean Golding
Title of project: 
Multi-omics analysis of nursery thermometer study
Proposal summary: 

During the last 6 months (May - Dec 1992) of recruitment to the study, mothers were randomised to receive a simple thermometer or not. Those who received one, were asked to place in the wall of the room where her baby slept (see project B4449 for further information). This project will investigate whether receiving a thermometer influences protein levels and DNA methylation.

Impact of research: 
This project will allow researchers to examine whether the presence of a thermometer in a child's bedroom may have an impact on children's inflammation levels and DNA methylation.
Date proposal received: 
Wednesday, 13 December, 2023
Date proposal approved: 
Monday, 18 December, 2023
Keywords: 
Epidemiology, Respiratory - asthma, Proteomics, Epigenetics