B4489 - Estimating the age-varying genetic association between the rs9939609 SNP at the FTO locus and body mass index BMI - 06/12/2023

B number: 
B4489
Principal applicant name: 
Kate Tilling | Population Health Sciences, Bristol Medical School (UK)
Co-applicants: 
Miss Panagiota Pagoni
Title of project: 
Estimating the age-varying genetic association between the rs9939609 SNP at the FTO locus and body mass index (BMI)
Proposal summary: 
Impact of research: 
Provide guidance on methods that could be used to combine summary-level data from studies that provide summary-level data on both SNP-phenotype associations and SNP by age interactions and studies that provide summary-level data only on the SNP-phenotype association.
Date proposal received: 
Wednesday, 6 December, 2023
Date proposal approved: 
Wednesday, 6 December, 2023
Keywords: 
Genetic epidemiology (including association studies and mendelian randomisation), Obesity, Computer simulations/modelling/algorithms, GWAS, Statistical methods, BMI, Genome wide association study