B4483 - Exploring the impact of cardiopulmonary fitness on exercise blood pressure cardiac output and peripheral blood flow - 06/12/2023

B number: 
B4483
Principal applicant name: 
Siana Jones | University College London (United Kingdom)
Co-applicants: 
Miss Annali Olivelle
Title of project: 
Exploring the impact of cardiopulmonary fitness on exercise blood pressure, cardiac output and peripheral blood flow
Proposal summary: 

Blood pressure rises during exercise as a result of changes in the amount of blood the heart pumps and changes in the circulation within skeletal muscle. An exaggerated blood pressure response to exercise can indicate poor cardiovascular health but recent work suggests an exaggerated exercise BP only indicates poor cardiovascular health when cardiopulmonary fitness (aerobic fitness) is low. In this project we propose to explore the effect of fitness on exercise blood pressure and the mechanisms underlying this relationship. Sex differences in all metrics and associations will also be explored to get a better understanding of cardiovascular health in young men and women.

Impact of research: 
Date proposal received: 
Monday, 4 December, 2023
Date proposal approved: 
Wednesday, 6 December, 2023
Keywords: 
Physiology, Statistical methods, Cardiovascular