B4435 - Understanding the aetiology of Childhood self-harm in the general population An epidemiological approach - 30/10/2023

B number: 
Principal applicant name: 
Robyn Wootton | University of Bristol, and Lovisenberg Hospital
Anastasia Izotova
Title of project: 
Understanding the aetiology of Childhood self-harm in the general population: An epidemiological approach
Proposal summary: 

The prevalence of self-harm in young people is increasing whilst the age of self-harm onset is decreasing. Prevention and early identification of self-harm is critical to prevent additional adverse outcomes. The majority of research to date has focused on self-harm during adolescence and adulthood. Little is known about the prevalence of childhood self-harm in the general population, its risk factors, and likely outcomes. The CHARM project is uniquely positioned to answer these questions, with data on self-harm behaviours in children as young as three and longitudinally up to age 16 years. This is combined with a wealth of longitudinal data including questionnaires, linkage to national health registries, genetic data, parent data and detailed environmental exposure data. The CHARM project will leverage this amazing resource to build the most detailed picture to date of emergence, persistence and aetiology of childhood self-harm in the general population. Furthermore, we will apply genetic epidemiology techniques to strengthen causal inference, which increases the likelihood of interventions being effective. Together, these analyses will paint a rich picture of an understudied phenotype and help inform intervention design to prevent childhood self-harm and consequently prevent later adverse outcomes.

Impact of research: 
Date proposal received: 
Tuesday, 10 October, 2023
Date proposal approved: 
Tuesday, 24 October, 2023
Mental health - Psychology, Psychiatry, Cognition, Mental health, Statistical methods, Childhood - childcare, childhood adversity