B4415 - Association of inflammation with cardiac structure in adolescents - 18/09/2023

B number: 
Principal applicant name: 
Andrew O. Agbaje | University of Eastern Finland (Finland)
Viivi Heijari
Title of project: 
Association of inflammation with cardiac structure in adolescents
Proposal summary: 

Increased left ventricular mass and hypertrophy has been associated with cardiovascular morbidities and mortality in later life. Often employed as surrogate for premature heart damage in the young population, increased left ventricular mass has been associated with risk factors such as elevated blood pressure, arterial stiffness. Recent study in a large cohort of adolescents reported that inflammation may precede early vascular damage in the causal path. It remains unclear whether inflammation associates with left ventricular mass in a large population of community dwelling adolescents who are apparently healthy. This undergraduate thesis will examine the cross-sectional association between inflammation and left ventricular mass/hypertrophy in 17 year old adolescents.

Impact of research: 
The research improves the understanding on the role of inflammation on cardiac structure in youthful life.
Date proposal received: 
Friday, 8 September, 2023
Date proposal approved: 
Monday, 18 September, 2023
Epidemiology, cardiovascular disease, Medical imaging, Cardiovascular