B4389 - Consortium Against Pain inEquality CAPE The impact of adverse childhood experiences on chronic pain responses to treatment - 21/08/2023

B number: 
Principal applicant name: 
Kate Timmins | University of Aberdeen
Prof Gary Macfarlane
Title of project: 
Consortium Against Pain inEquality (CAPE): The impact of adverse childhood experiences on chronic pain & responses to treatment
Proposal summary: 

Having a traumatic experience as a child – for example, abuse or deprivation – can have a lifelong impact. People who report having several adverse childhood experiences, or ACEs, are more likely to have health problems later in life.

The Consortium Against Pain InEquality (CAPE) aims to further understand how ACEs might lead to chronic pain in adulthood. We want to consider how other factors (such as mental health or support from friends or family) contribute to pain vulnerability. Our main question is: Do ACEs cause an increased risk of chronic pain in later life, and, if so, what roles do other factors play?

Using existing data from several cohorts, of which the Avon Longitudinal Study of Parents and Children is one, we will run analyses to better understand the factors that may contribute to, or protect against, developing chronic pain, trying to describe the different ways ACEs (of different types, number and characteristics) may be linked to chronic pain (‘causal pathways’).

Impact of research: 
The outputs hope to confirm or elaborate on the causal relationship between ACEs and pain. A better understanding of mechanisms could enable the identification of opportunities where preventative efforts could be focused, as well as providing evidence to underpin the development of trauma-informed practices in pain diagnosis and management.
Date proposal received: 
Thursday, 3 August, 2023
Date proposal approved: 
Monday, 14 August, 2023
Epidemiology, Pain, Childhood - childcare, childhood adversity