B4219 - KidImmune - Autoimmunity in pediatric cancer 08-12-2022 - 123122 - 18/07/2023
B number:
B4219
Principal applicant name:
Ola Myklebost | University of Bergen
Co-applicants:
Title of project:
KidImmune, - Autoimmunity in pediatric cancer (08-12-2022 - 12:31:22)
Proposal summary:
We have identified a proteomic pattern in serum from a major fraction of pediatric cancer patients that we do not see in healthy controls and only occasionally in adult patients. We suspect this pattern is associated with a risk of cancer rather than being a consequence of the disease, and for this purpose we are searching for biobanks with blood samples from healthy children who later contracted cancer, to see if the pattern can be identified before cancer appears.
Impact of research:
If we can demonstrate the presence of these biomarkers before cancer diagnosis, it is the closest we can come to proving our hypothesis that these biomarkers define a predisposition phenotype that may cause cancer. This would be very high impact, a new etiology of pediatric cancer.
Date proposal received:
Monday, 12 December, 2022
Date proposal approved:
Wednesday, 14 December, 2022
Keywords:
Cancer etiology, Cancer, Microarrays, Proteomics, Biological samples -e.g. blood, cell lines, saliva, etc., Immunity