B4334 - Characterising determinants of early growth trajectories and their consequences on later life health - 05/06/2023
B number:
B4334
Principal applicant name:
Nicole Warrington | University of Queensland Institute for Molecular Bioscience (Australia)
Co-applicants:
Kym-Mai Nguyen, Prof David Evans
Title of project:
Characterising determinants of early growth trajectories and their consequences on later life health
Proposal summary:
The prevalence of cardiovascular disease and diabetes is increasing and the financial burden on society is substantial. Children who have unfavourable growth through early life are at increased risk of these diseases. This study aims to investigate the relationship between early life growth and future risk of diseases like diabetes and perform a large study looking at the relationship between methylation and growth. Knowledge gained from these studies will inform the design of public health initiatives.
Impact of research:
Date proposal received:
Monday, 29 May, 2023
Date proposal approved:
Monday, 5 June, 2023
Keywords:
Genetic epidemiology (including association studies and mendelian randomisation), Diabetes, Hypertension, Mental health, Obesity, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Gene mapping, GWAS, Proteomics, Statistical methods, Birth outcomes, Blood pressure, Mendelian randomisation, Mothers - maternal age, menopause, obstetrics, Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc., Offspring, Puberty, Statistical methods, BMI, Cardiovascular, Development, Epigenetics, Genetic epidemiology, Genetics, Genome wide association study, Growth