B4312 - Association of child maltreatment and neurodevelopmental traits with cardiometabolic markers in young adults - 03/05/2023

B number: 
B4312
Principal applicant name: 
Daniel Kerr | University of Glasgow (UK)
Co-applicants: 
Prof Helen Minnis
Title of project: 
Association of child maltreatment and neurodevelopmental traits with cardiometabolic markers in young adults
Proposal summary: 

Child maltreatment and childhood neurodevelopmental disorders (Autism and ADHD) are both associated with increased risk of cardiovascular disease and premature mortality in adulthood. Child maltreatment and neurodevelopmental disorders commonly co-occur. Previous work has explored the associations of these exposures individually with adult outcomes but not explored them together. This study aims to explore the association of neurodevelopment and maltreatment with cardiovascular risk factors in young adults, in particular looking for any interaction between the two exposures.

Impact of research: 
Explore relative impacts of maltreatment and/or neurodevelopmental disorder on cardiovascular risk. Strengthen and guide importance of developing risk stratification for exposed individuals.
Date proposal received: 
Wednesday, 19 April, 2023
Date proposal approved: 
Wednesday, 3 May, 2023
Keywords: 
Epidemiology, Developmental disorders - autism, Diabetes, Hypertension, Mental health, Obesity, Statistical methods, Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Blood pressure, BMI, Cardiovascular, Cohort studies - attrition, bias, participant engagement, ethics