B4310 - Meta-ewas of breast feeding - 24/04/2023

B number: 
Principal applicant name: 
Hannah Elliott | University of Bristol (United Kingdom)
Dr Doretta Caramaschi
Title of project: 
Meta-ewas of breast feeding
Proposal summary: 

This project aims to assess the association between DNA methylation and breastfeeding using data from ALSPAC and other birth cohorts with similar data. Breastfeeding has both short and long term beneficial effects on child health. DNA methylation is a molecular mechanism which might mediate the relationship between breast feeding and beneficial health effects in children but we do not yet have good evidence to show if DNA methylation is associated with breast feeding. This research aims to answer this knowledge gap.

Impact of research: 
This research will result in an open access peer reviewed paper which will determine the relationship between DNA methylation and breastfeeding outcomes.
Date proposal received: 
Wednesday, 19 April, 2023
Date proposal approved: 
Monday, 24 April, 2023
Epidemiology, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., EWAS, Biological samples -e.g. blood, cell lines, saliva, etc., Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Birth outcomes, Breast feeding