B4264 - Understanding social inequalities in childhood asthma a pilot study - 28/02/2023

B number: 
Principal applicant name: 
Angela Pinot de Moira | National Heart and Lung Institute, Imperial College London (UK)
Title of project: 
Understanding social inequalities in childhood asthma: a pilot study
Proposal summary: 

Asthma is the most common chronic disease affecting children. It is also a complex disease, coming in different forms with different underlying causes or mechanisms. Although we do not fully understand what causes asthma, there is good evidence that social conditions early in a child’s life play an important role in its development. Children from poorer backgrounds are more likely to develop asthma, suffer from asthma attacks, require hospitalisation and die from their asthma. However, few studies have explored to what extent different types of asthma are affected by socio-economic conditions in early life.
This study will examine the social distribution of different types of asthma and investigate to what extent specific early-life risk factors explain observed social inequalities.

Impact of research: 
This study will improve our understanding of the nature of social inequalities in asthma, including how different asthma phenotypes are socially patterned and what mediators could be targeted by interventions aimed at reducing social inequalities in asthma. This will ultimately help to reduce unfair differences in asthma risk and reduce costs to health care systems.
Date proposal received: 
Sunday, 19 February, 2023
Date proposal approved: 
Tuesday, 28 February, 2023
Epidemiology, Respiratory - asthma, Statistical methods, Breast feeding, Childhood - childcare, childhood adversity, Environment - enviromental exposure, pollution, Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc.