B4013 - Asthma Phenotypes and Sputum Biomarkers in High- Medium- and Low-Income Countries - 09/03/2022

B number: 
Principal applicant name: 
Collin Brooks | Massey University (Research Centre for Hauora and Health) (New Zealand)
Mr Jeroen Burmanje
Title of project: 
Asthma Phenotypes and Sputum Biomarkers in High-, Medium- and Low-Income Countries
Proposal summary: 

Asthma remains a major global public health concern. However, asthma prevalence is different in high-income countries (HICs) and low and middle-income countries (LMICs), and what we know about asthma pathology is generally based on studies in HICs. To address this, the World Asthma Phenotypes Study (WASP) study started in 2016 to better understand types of asthma in five centres around the world; the UK (Bristol: ALSPAC), New Zealand, Brazil, Ecuador, and Uganda. The main objective of this specific project (which is part of WASP) is to focus on the association between soluble airway biomarkers, patterns of airway inflammation, and clinical characteristics, to better understand and characterise types of asthma in the different centres.

Impact of research: 
Date proposal received: 
Wednesday, 23 February, 2022
Date proposal approved: 
Wednesday, 9 March, 2022
Epidemiology, Respiratory - asthma, Enzyme-Linked Immunosorbent Assay (ELISA) and multiplex bead array assays using the Luminex MAGPIX., Biological samples -e.g. blood, cell lines, saliva, etc., Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc.