B3966 - Stratification of ADHD developmental trajectories with evidence from environmental risk factors epi-genetics and neuroimaging - 28/02/2022
B number:
B3966
Principal applicant name:
Jianfeng Feng | Fudan University (china)
Co-applicants:
Dr Tianye Jia
Title of project:
Stratification of ADHD developmental trajectories with evidence from environmental risk factors, (epi-)genetics and neuroimaging
Proposal summary:
Individuals with attention deficit hyperactivity disorder (ADHD) may undergo different developmental trajectories throughout adolescence. Previous evidence has indicated that neural signatures and genetics could help to distinguish individuals with persistent ADHD symptoms from those remitted. However, little evidence has been provided to demonstrate whether environmental risk factors, such as substance use, could also affect the development of ADHD symptoms.
Impact of research:
This study will advance our understanding of the cause between environmental risk factors, (epi-)genetics, and neuroimaging and ADHD, which may reshape future clinical practice. Our study may also help establish a unified approach in understanding the neurobiological mechanism of other neurodevelopmental disorders.
Date proposal received:
Wednesday, 12 January, 2022
Date proposal approved:
Monday, 28 February, 2022
Keywords:
Mental health - Psychology, Psychiatry, Cognition, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Medical imaging, Equipment - MRI