B3919 - Investigating the mechanisms underlying sleep problems and links to mental ill health in autistic children and adolescents - 01/11/2021

B number: 
B3919
Principal applicant name: 
Daniel Smith | University of Edinburgh (United Kingdom)
Co-applicants: 
Ms. Reesha Zahir, Prof. Sue Fletcher-Watson
Title of project: 
Investigating the mechanisms underlying sleep problems and links to mental ill health in autistic children and adolescents
Proposal summary: 

Disordered sleep is commonly reported in autism from a young age, as are symptoms of mental illness. Mental health and sleep are known to influence each other in a bidirectional manner within the general population, but the nature of the association between sleep and mental health problems in autism is poorly understood. Moreover, the underlying causes of sleep problems in autism are unknown. Thus, current treatments for sleep problems are largely ineffective in autistic people, and they also face severe consequences of mental ill health, such as high rates of suicidality and in-patient care. We aim to characterise the relationship between sleep problems and mental ill health, and identify factors underpinning the sleep problems in autism and in people with autistic traits. We will focus specifically on childhood and adolescence as this comprises the typical age-range of onset for problems in both sleep and mental health. Our approach to answering these questions will involve statistical modelling of longitudinal data on sleep and mental health in ALSPAC.

Impact of research: 
By increasing our understanding of the mechanisms underpinning sleep problems in autism, this research could help inform treatment approaches, as well as the development of new interventions to improve sleep in autistic people. Moreover, characterising the contribution of sleep to mental health in autism could also help address mental illness in autism more effectively, thus improving both mental health and quality of life outcomes for autistic people
Date proposal received: 
Wednesday, 27 October, 2021
Date proposal approved: 
Thursday, 28 October, 2021
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Developmental disorders - autism, Statistical methods, Statistical methods