B3826 - Association of Fat Mass Index FMI and DNA metyhylation - from childhood to adolescence - 12/07/2021

B number: 
B3826
Principal applicant name: 
Giulia Mancano | IEU, University of Bristol
Co-applicants: 
Dr Gemma Sharp, Dr Janine F. Felix, Giulietta Monasso
Title of project: 
Association of Fat Mass Index (FMI) and DNA metyhylation - from childhood to adolescence
Proposal summary: 

Obesity has been extensively linked to a plethora of health conditions, but most research has defined obesity using body mass index (BMI). While BMI may be a very straightforward and useful marker of obesity, recent research suggest that a targeted measurement of one's fat, in the form of fat mass index (FMI), might be a more clinically relevant measure.

Impact of research: 
Build evidence on the link between fat mass and DNA methylation and on the mechanistic pathway linking fat mass to adverse health outcomes
Date proposal received: 
Wednesday, 7 July, 2021
Date proposal approved: 
Monday, 12 July, 2021
Keywords: 
Epigenetic Epidemiology, Obesity, EWAS, DNA methylation Offspring Child fat mass Index