B3739 - Prevalence of ideal cardiovascular health in preschoolers early determinants and associations with neurodevelopment - 29/03/2021

B number: 
Principal applicant name: 
HEUDE | INSERM (France) (France)
EMPANA Jean-Philippe, Dr, TAFFLET Muriel, Mrs, CLIMIE Rachel, Dr, CHARLES Marie-Aline,Dr
Title of project: 
Prevalence of ideal cardiovascular health in preschoolers, early determinants and associations with neurodevelopment
Proposal summary: 

In the context of the concept of primordial prevention, a score of ideal cardiovascular health has been defined by the American Heart Association (Lloyd Jones et al. 2010). In adults, a higher score as been associated to a Incident Cardiovascular Events, lower Cognitive Decline and Incident Dementia (van Sloten et al. 2018; Samieri et al. 2018). This score relies on the combination of “ideal” values for 7 metrics from cardiometabolic health and behaviours. Ideal values will be defined as recommended values from previous studies and/or from internal thresholds. The list of the 7 metrics entering the score is as follows: Body mass index, physical activity, healthy diet, smoking, blood pressure, fasting plasma glucose, total cholesterol. Two sub-scores can be computed, one from the behavioural components (BMI, physical activity, diet and smoking), and the other from the clinical and biological components (blood pressure, glucose and cholesterol).

Impact of research: 
Date proposal received: 
Tuesday, 16 March, 2021
Date proposal approved: 
Monday, 22 March, 2021
Epidemiology, Blood pressure, BMI, Cardiovascular, Cognition - cognitive function, Development, Nutrition - breast feeding, diet, Physical - activity, fitness, function