B3731 - Feasibility assessment of RNA sequencing of blood spots - 22/03/2021
B number:
B3731
Principal applicant name:
Jennifer Silvers | University of California, Los Angeles
Co-applicants:
Steve Cole
Title of project:
Feasibility assessment of RNA sequencing of blood spots
Proposal summary:
We are seeking to test the feasibility of doing RNA sequencing on blood spots as collected in the ALSPAC study. We have done this type of analysis on dry blood spots before but not on blood that was collected in a tube and then put on paper. We want to ensure the samples are viable for our planned analyses.
Impact of research:
The feasibility analysis would inform whether the planned eventual research is possible. The planned future research would be the first to examine longitudinal changes in immune system markers across 3 timepoints in development. This could fundamentally shape our knowledge of neuroimmune functioning and launch a broader series of studies to examine how childhood experiences shape inflammatory disease.
Date proposal received:
Thursday, 4 March, 2021
Date proposal approved:
Monday, 8 March, 2021
Keywords:
Immunology, RNA, Biological samples -e.g. blood, cell lines, saliva, etc., Development