B3694 - Epigenome-wide association study of handedness - 06/01/2021

B number: 
Principal applicant name: 
Matthew Suderman | University of Bristol (United Kingdom)
Veronika Odintsova
Title of project: 
Epigenome-wide association study of handedness
Proposal summary: 

Hand preference is only weakly determined by genetics. Consequently, environment likely plays a role by modifying the expression of certain genes during early development. In this study, we will ask to what extent DNA methylation, a well-known regulator of genes, is associated with hand preference in ALSPAC children and their parents beyond known genetic associations.

Impact of research: 
Improved understanding of the relationship between DNA methylation and handedness.
Date proposal received: 
Monday, 4 January, 2021
Date proposal approved: 
Wednesday, 6 January, 2021
Developmental biology, hand preference, Microarrays, Development, Epigenetics, Handedness