B3668 - The relationship between parenting and mental health the role of genetic nurture and child evocative effects across contexts - 02/12/2020
B number:
B3668
Principal applicant name:
Marcus Munafò | University of Bristol
Co-applicants:
Miss Amy Campbell, Dr Hannah Sallis, Dr Rebecca Pearson
Title of project:
The relationship between parenting and mental health: the role of genetic nurture and child evocative effects across contexts
Proposal summary:
There are known links between parenting behaviour and mental health outcomes in children. However, it is not known the extent to which the genetics of the mother and the child independently interact to influence children’s future mental health. Genetics can influence child outcomes in multiple different ways:
1. Genetic variants which increase the risk of developing a mental health disorder can be passed directly from mother to child
2. A mother’s genetics can affect the way that she parents her child
3. A child’s genetics can cause them to behave in certain ways which evoke certain responses from their mother
Across four studies, I will investigate the role of genetics in the relationship between parenting and mental health outcomes.
Impact of research:
This PhD will contribute to the overall understanding of the intergenerational transmission of mental health, through parenting and genetic factors. This improved aetiological understanding can then facilitate identification of intervention targets and intervention design.
Date proposal received:
Monday, 30 November, 2020
Date proposal approved:
Wednesday, 2 December, 2020
Keywords:
Genetic epidemiology (including association studies and mendelian randomisation), Mental health, Computer simulations/modelling/algorithms, Psychology - personality