B3568 - The genetics of speech sound disorder - 13/07/2020

B number: 
Principal applicant name: 
Yvonne E Wren | University of Bristol (UK)
Professor Angela Morgan, Dr Dianne Newbury
Title of project: 
The genetics of speech sound disorder
Proposal summary: 

There is variation in when and how children develop speech in early childhood. Some children experience difficulties in the process but many of these have speech which is well developed by the time they start school. Some children have persistent problems which continue into early childhood. These problems can be associated with problems with educational attainment in older childhood as well as having difficulties in making themselves understood. Some of these children will have problems with their speech as a result of subtle problems with the coordination of the movements required for speech while others will have difficulties associated with the cognitive skills involved in developing speech. Some will have problems with both.
Genes have been identified which are associated with some types of speech and language difficulties but it is not yet clear what part genes may play in persistent speech sound disorder. The analysis outlined in this proposal will enable us to determine to what extent children's problems with speech after they have started school may be associated with genetic factors rather than environmental factors. This information will help us identify how best to help children who present with these difficulties to speech and language therapists and in school.

Impact of research: 
An understanding of the genetic basis for persistent speech sound disorder
Date proposal received: 
Thursday, 9 July, 2020
Date proposal approved: 
Monday, 13 July, 2020
Genetics, Speech/language problem, Gene mapping, Speech and language