B3561 - Exploring how much complex trait variation is captured by DNA methylation in epigenome-wide association studies - 23/06/2020
B number:
B3561
Principal applicant name:
Gibran Hemani | MRC IEU
Co-applicants:
Mr. Thomas Battram, Professor Tom Gaunt, Professor Nicholas Timpson
Title of project:
Exploring how much complex trait variation is captured by DNA methylation in epigenome-wide association studies
Proposal summary:
There are small chemicals that can be added to or removed from genes. These chemical changes may be related to changes in various human traits. For example smoking may cause a decrease in the number of these chemicals present at one or many genes. Currently it is not fully understood how these chemical changes are related to changes in human traits and this project aims to assess how chemical changes across many genes may relate to changes in human traits.
Impact of research:
Date proposal received:
Monday, 22 June, 2020
Keywords:
Molecular genetics and genomics, Microarrays, Epigenetics