B3496 - Understanding the intergenerational transmission of risk for offspring mental health cognitive and educational outcomes - 20/04/2020

B number: 
B3496
Principal applicant name: 
Jean-Baptiste Pingault | Department of Clinical, Educational and Health Psychology University College London (UK)
Co-applicants: 
Dr Biyao Wang, Dr Biyao Wang
Title of project: 
Understanding the intergenerational transmission of risk for offspring mental health, cognitive and educational outcomes
Proposal summary: 

Parental risk factors are among the strongest early predictors of offspring mental health, cognitive and educational outcomes. This transmission of risk across generations hinders social mobility. Interventions targeting parents may thus appear promising. However, such interventions can only succeed if the relationship between parental risks and offspring outcomes are causal, which remains unclear. Here, we propose to use genetically informed design to better characterize the intergenerational pathways underlying risk transmission.

Impact of research: 
Outcome 1: Policy impact. Our project will provide further insights into aspects of the home environment that could be targeted in future preventive interventions. To maximize impact, we will work with The Early Intervention and the Nuffield foundations, in addition to UCL Policy Impact. Outcome 2: Academic impact. Several articles will be delivered, aiming for high impact publications, along with exposure at national and two international conferences. Outcome 3: Contribute to scientific education. We will engage the wider public through the following pathways: (i) communicate research findings through cohort specific mechanisms; (ii) collaborating with the dedicated communication teams at the Centre for Longitudinal Study and the wider UCL to write press releases; (iii)
Date proposal received: 
Monday, 6 April, 2020
Date proposal approved: 
Monday, 6 April, 2020
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, The project does not focus on diseases but rather adopts a dimensional perspective on different domains of child and adolescent development. , Statistical methods, Cognition - cognitive function, Development, Fathers, Genetic epidemiology, Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc., Offspring, Parenting, Psychology - personality