B3412 - Environmental exposures in pregnancy and early life influencing cognitive and cardio-respiratory development - 24/11/2019
B number:
B3412
Principal applicant name:
Anna Hansell | University of Leicester, Centre for Environmental Health and Sustainability (United Kingdom)
Co-applicants:
Miss Yingxin Chen, Miss Katie Eminson, Professor John Gulliver, Dr Calvin Jephcote
Title of project:
Environmental exposures in pregnancy and early life influencing cognitive and cardio-respiratory development
Proposal summary:
Exposure to air pollution and road transport noise in pregnancy and early life may affect development of heart, lung and cognitive function that have long-term effects into adult life. However, it is unclear how important this is as there are few studies on the impact of very early life exposures to environmental pollution
Impact of research:
The findings of this project will provide new knowledge to inform UK and European policy, with relevance to design and placement of new housing, schools and roads, and to noise and air pollution abatement schemes. Dissemination will be through our existing links with the Noise and Nuisance Technical and Evidence Team at DEFRA, through candidate attendance at international conferences (International Commission for the Biological Effects of Noise conference in 2020 and the Internoise conference 2021) and publication of peer-reviewed journal papers.
It is intended to publish results in high impact journals at the end of the project, which might contribute to policy decision-making and/or future follow-up studies.
Date proposal received:
Monday, 18 November, 2019
Date proposal approved:
Tuesday, 19 November, 2019
Keywords:
Epidemiology, Developmental disorders - autism, Cognitive impairment, Diabetes, Hypertension, Learning difficulty, Mental health, Respiratory - asthma, Speech/language problem, CVDs, lung function, Computer simulations/modelling/algorithms, Statistical methods, Cardiovascular, Cohort studies - attrition, bias, participant engagement, ethics, Mothers - maternal age, menopause, obstetrics, Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc., Nutrition - breast feeding, diet, Offspring, Parenting, Psychology - personality, Physical - activity, fitness, function, Social science, Speech and language, Statistical methods, Childhood - childcare, childhood adversity, Cognition - cognitive function, Communication (including non-verbal), Development, Environment - enviromental exposure, pollution, Growth, Intelligence - memory, Linkage