B3408 - International Cannabis Consortium - GWAMA of quantity/frequency of cannabis use - 14/11/2019
B number:
B3408
Principal applicant name:
Lindsey Hines | Population Health Sciences
Co-applicants:
Dr Robyn Wootton, Dr Hannah Sallis, Professor Marcus Munafo
Title of project:
International Cannabis Consortium - GWAMA of quantity/frequency of cannabis use
Proposal summary:
The International Cannabis Consortium has been created to combine the results of multiple genome-wide association studies of different cannabis use phenotypes (e.g., lifetime use, age at initiation, frequency of cannabis use) in meta-analyses in order to increase the probability of detection of genetic variants associated with individual differences in cannabis use.
Impact of research:
The consortium has published several successful GWAS meta-analyses over the years, including lifetime use and age at initiation. This it the first meta-analysis on the frequency of cannabis use. Frequency of use is a key determinant of the harms of cannabis use, and developing the GWAS for this phenotype is critical for understanding the relationship between cannabis and mental health.
Date proposal received:
Wednesday, 13 November, 2019
Date proposal approved:
Thursday, 14 November, 2019
Keywords:
Genetics, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Mental health, GWAS, Genome wide association study