B3388 - Dietary intake throughout childhood and adolescence with cardiometabolic health in later life - 04/10/2019

B number: 
B3388
Principal applicant name: 
Kaitlin Wade | MRC-IEU, University of Bristol (United Kingdom)
Co-applicants: 
Dr Emma Anderson, Rosie Fraser
Title of project: 
Dietary intake throughout childhood and adolescence with cardiometabolic health in later life
Proposal summary: 

The aim of this study is to assess the association between dietary intake measured throughout childhood and early adolescence and later cardiometabolic health within a large population.

Impact of research: 
It is currently unclear whether there are sensitive periods during early life that whereby diet has impact cardiometabolic health later in life. Additionally, most studies assessing the impact of childhood nutrition on later health are either of cross-sectional or short-term prospective design, most of which focus on a specific period (e.g., infancy) and are usually restricted to one measure of dietary intake. Repeated measure data is necessary to determine whether there are sensitive periods of early life during which dietary intake is particularly strongly related to later cardiometabolic health to identify suitable target ages for dietary intervention. In parallel, the mechanism by which dietary intake is associated with cardiovascular health requires interrogation, in order to develop more focused strategies aimed to prevent later adverse cardiovascular health.
Date proposal received: 
Thursday, 3 October, 2019
Date proposal approved: 
Friday, 4 October, 2019
Keywords: 
Epidemiology, Obesity, cardiovascular health, Statistical methods, Blood pressure, BMI, Cardiovascular, Childhood - childcare, childhood adversity, Statistical methods