B3356 - GWAS of breast density - 09/08/2019

B number: 
B3356
Principal applicant name: 
Caroline Bull | MRC IEU, University of Bristol
Co-applicants: 
Professor Nic Timpson, Dr Emma Vincent, Dr Bethan Lloyd-Lewis, Dr David Hughes
Title of project: 
GWAS of breast density
Proposal summary: 

Increased breast density is strongly associated with increased breast cancer risk, however, the underlying biology is unclear.
We aim to identify genetic variation associated with breast density to help explain this association.

Impact of research: 
Date proposal received: 
Friday, 9 August, 2019
Date proposal approved: 
Friday, 9 August, 2019
Keywords: 
Genetic epidemiology (including association studies and mendelian randomisation), Cancer, GWAS, Cohort studies - attrition, bias, participant engagement, ethics, Development, Genetic epidemiology, Genetics, Genome wide association study, Mendelian randomisation