Atopic dermatitis (AD), also known as eczema, is a chronic, itchy skin disorder that affects up to 20% of children. It has been associated with neuropsychiatric disorders such as depression, anxiety, and attention deficit hyperactivity disorder. Previous studies have shown higher rates of sleep disruption, inattention, and forgetfulness in children with AD compared to those without AD; these suggest that neurocognition, which encompasses functions such as language, memory, attention, and executive functions, may be impacted by AD. However, there are few studies of cognition in children with AD. Previous studies have also been limited by small sample size and have shown mixed findings. Thus, the purpose of this study is to compare neurocognitive function between children with and without AD using the large ALSPAC cohort. We will comprehensively assess multiple domains of cognition (e.g. attention, executive function, memory, IQ) using validated and standardized measurements. We will examine the overall impact of AD on these cognitive outcomes, accounting for demographic and socioeconomic factors and other comorbidities. In addition, we will examine whether cognitive function differs with respect to AD disease activity.