B3278 - Understanding the multimorbidity of non-communicable diseases from childhood to adulthood MOCHA - 25/03/2019
B number:
B3278
Principal applicant name:
Raquel Granell | IEU Population Health Sciences Bristol Medical School (United Kingdom)
Co-applicants:
Prof John Henderson
Title of project:
Understanding the multimorbidity of non-communicable diseases from childhood to adulthood (MOCHA)
Proposal summary:
Multimorbidity (i.e. the co-occurrence of more than one chronic disease in the same person) has been recognised as
a major public health problem in the old age. In contrast, knowledge of multimorbidity among children,
adolescents and young adults is lacking. MOCHA challenges the prevailing concept that multimorbidity is
mainly an issue of ageing. MOCHA hypothesises that multimorbidity originates early in life and continues to develop throughout the life
course.
Impact of research:
Publications in high impact relevant journals
Date proposal received:
Thursday, 21 March, 2019
Date proposal approved:
Monday, 25 March, 2019
Keywords:
Genetic epidemiology (including association studies and mendelian randomisation), Allergy, Eczema, Mental health, Obesity, Respiratory - asthma, GWAS, Ageing, Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Genetics, Genome wide association study, Hormones - cortisol, IGF, thyroid, Mendelian randomisation, Puberty, Birth outcomes, Blood pressure, BMI, Breast feeding, Cardiovascular, Cognition - cognitive function, Epigenetics, Genetic epidemiology