B3114 - Tracking Sleep Phenotypes 2 15-05-2018 - 234902 - 26/05/2018

B number: 
B3114
Principal applicant name: 
Helen Heussler | Center for CHildren's Health Research. University of Qld (Australia)
Co-applicants: 
Emily Sawyer, Prof Karen Thorpe, Simon Smith , Ronny Gunnarson, Mamun Abdullah, Enda Byrne, Adam Ewing, Peter Blair
Title of project: 
Tracking Sleep Phenotypes (2) (15-05-2018 - 23:49:02)
Proposal summary: 

Sleep matters to those who care for young children. The duration and timing of sleep can have a profound effect on a young child’s everyday behaviour, learning and health and also has a significant impact on the routines and wellbeing of the adults who provide his or her care. Yet there is surprisingly little evidence regarding the developmental function of early sleep patterns. Current understanding of the processes underpinning normative transition in sleep patterns, the prevalence of specific sleep phenotypes and persistence in sleep patterns across time is limited. This study will utilise genetic and environmental data, alongside longitudinal sleep data to examine the prevalence, persistence and developmental significance of childhood sleep phenotypes.

This knowledge will inform clinical, public health and educational policy and practice where management of sleep is an issue of controversy and also inform parenting practice where early child sleep behaviours can have a major impact on family functioning, parent well-being and child development.

Impact of research: 
The focus of our research will be important in informing care practices particularly in early childhood settings and family contexts. Internationally the importance of sleep in long term health is growing but the available evidence and subsequent evidence for policy and practice is limited. In Australia and the US for example while there are significant recommendations for exercise and nutrition in young children the existing sleep recommendations are limited to sleep safety in the first year. (We are pleased to have Prof Peter Blair on the Team) Longitudinally the existence of tight phenotypes has been challenging to establish however using this data we hope to establish some genotype- phenotype relationships to help inform practice.
Date proposal received: 
Thursday, 17 May, 2018
Keywords: 
Clinical research/clinical practice, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Developmental disorders - autism, Cognitive impairment, Mental health, DNA sequencing, GWAS, Childhood - childcare, childhood adversity, Cognition - cognitive function, Development, Environment - enviromental exposure, pollution, Epigenetics, Genomics, Intelligence - memory, Sleep