B110 - Bladder and bowel continence - 01/05/2003

B number: 
Principal applicant name: 
Prof Jean Golding (University of Bristol, UK)
Title of project: 
Bladder and bowel continence.
Proposal summary: 

Generalised Growth Mixture Models will enable us to divide the children into different groups (cluster-analysis style) and fit a different trajectory for each group. In the graph below, the y-axis is the probability of being dry at night. Preliminary analysis using data up to 91 months suggests 4 different groups: normal children, delayed dryness, severely delayed dryness and a relapse group.

Group membership can then be used as either a multinomial outcome or as a predictor for further analysis into the causes/effects of subnormal development of continence. The intention is to produce one methodological paper on the subject of fitting such models and then further epidemiological papers using the resulting groups.

Date proposal received: 
Thursday, 1 May, 2003
Date proposal approved: 
Thursday, 1 May, 2003
Primary keyword: