B449 - Translating genome-wide association data from the WTCCC study into biological and clinical insights in type 2 diabetes - 01/09/2006

B number: 
B449
Principal applicant name: 
Prof Tim Frayling (University of Exeter & Plymouth, UK)
Co-applicants: 
Prof David McCarthy (London Metropole University, UK), Dr Michael Weedon (Peninsula Medical School, University of Plymouth, UK), Prof Andrew Hattersley (Not used 0, Not used 0)
Title of project: 
Translating genome-wide association data from the WTCCC study into biological and clinical insights in type 2 diabetes
Proposal summary: 

Aim.

To test the hypothesis that variation in genes in key beta-cell pathways increases the risk of type 2 diabetes.

Aim: To use large-scale genome wide association data from the Wellcome Trust Case Control Consortium (WTCCC) as a platform for a systematic assessment of the role of variation in beta-cell genes in the aetiology of type 2 diabetes.

Date proposal received: 
Friday, 1 September, 2006
Date proposal approved: 
Friday, 1 September, 2006
Keywords: 
Primary keyword: