We would like to conduct a study into the longer-term behavioural outcomes of prenatal exposure to alcohol and the potential modifying influences of maternal and child metabolising genes. Although this is a topic of considerable public health importance, only a handful of studies, conducted in small convenience samples, have been conducted to date and many questions remain unanswered (please see scientific outline). ALSPAC is ultimately suited for such a study because it is large, population-based, a wealth of data already exists on pregnancy as well as offspring development throughout childhood and adolescence, while DNA has already been obtained as well.