B600 - Investigation of the role of bone size relative to body size in the pathogenesis of fractures in childhood
B number:
B600
Principal applicant name:
Dr Jon Tobias (University of Bristol, UK)
Co-applicants:
Title of project:
Investigation of the role of bone size relative to body size in the pathogenesis of fractures in childhood
Proposal summary:
Aims
(i) Whether changes in bone size relative to body size contribute to the increased risk of fracture during puberty will be established, by examining the relationship between longitudinal changes in these parameters across puberty.
(ii) Whether the higher risk of fracture in pubertal boys compared to girls is related to gender differences in bone size relative to body size will be determined.
(iii) Whether small bone size relative to body size represents a stable trait that once established in childhood persists following puberty will be investigated.
Date proposal received:
Friday, 18 January, 2008
Keywords:
Primary keyword: