B682 - Risk Factors and outcomes associated with bedwetting daytime wetting and soiling in late childhood and early adolesence - 04/08/2008

B number: 
B682
Principal applicant name: 
Dr Carol Joinson (University of Bristol, UK)
Co-applicants: 
Penny Dobson (University of Bristol, UK), Dr Jon Heron (University of Bristol, UK)
Title of project: 
Risk Factors and outcomes associated with bedwetting, daytime wetting and soiling in late childhood and early adolesence
Proposal summary: 

Summary

The overall aim is to increase an understanding of the impact of nocturnal enuresis, day wetting and soiling in late childhood/early adolescence (9-13 years) and to examine risk factors for persistent wetting and soiling in a prospective cohort study - the Avon Longitudinal Study of Parents and Children (ALSPAC). The two main threads are:

(i) the impact of persistent wetting/soiling problems on the everyday life of young adolescents on outcomes,including mental health, education/school attainment, peer relationships, social activities and goals/aspirations for the future

(ii) the risk factors for wetting and soiling problems continuing through the period of late childhood and into early adolescence

Within these threads, the specific research questions of the proposed project are:

Impact of wetting and soiling

* Do children with persistent wetting/soiling at 13 years have a higher risk of problems with mental health, self concept / image, education/school attainment, peer relationships and leisure activities than those with delayed bladder/bowel control (wetting/soiling that resolved during the period 9-13 years)?

* Are there long lasting negative outcomes associated with experiencing a delay in attainment of bladder/bowel control, or do the problems improve/resolve following resolution of wetting/soiling?

* Does the impact of wetting/soiling problems become more acute or distressing in late childhood/early adolescence compared to earlier childhood?

* Are adolescents with combined problems (wetting and soiling) at increased risk of negative outcomes compared to those with wetting or soiling alone?

Risk factors

* What is the impact and timing of negative life events on trajectories of bladder/bowel control?

* Is there an increased vulnerability to negative outcomes in children with wetting/soiling who experience socioeconomic disadvantage

* Does onset of puberty have an impact on wetting/soiling problems? Is puberty associated with a resolution of wetting/soiling?)

* Is there a higher rate of cognitive impairments in children with persistent wetting/soiling compared to delayed bladder/bowel control?

Date proposal received: 
Monday, 4 August, 2008
Date proposal approved: 
Monday, 4 August, 2008
Keywords: 
Risks
Primary keyword: