B697 - A genome-wide association study of ankylosing spondylitis risk - 01/01/1900
B number:
B697
Principal applicant name:
Dr Dave Evans (Not used 0, Not used 0)
Co-applicants:
Matt Brown (Not used 0, Not used 0), Prof John Reveille (Not used 0, Not used 0)
Title of project:
A genome-wide association study of ankylosing spondylitis risk
Proposal summary:
We have performed a large genome-wide association study in a few thousand ankylosing spondylitis patients and need to replicate several promising genetic associations. Although we have genotyped putatively associated SNPs in a new sample of cases, we need to obtain genotype data from a similarly sized european control sample on ~100 candidate SNPs. Since both cohorts have been genotyped on the Illumina 317K SNP chip, the ~1700 ALSPAC individuals for whom genome-wide SNP data is now available would be an obvious choice. Note that we are requesting a small number of candidate SNPs (i.e. ~100 SNPs) NOT the entire genome-wide dataset.
Date proposal received:
Friday, 5 September, 2008
Date proposal approved:
Monday, 1 January, 1900
Keywords:
Genetics
Primary keyword: