B732 - Follow-up analysis of signals associated with early developmental traits ALSPAC GWAS within the complete ALSPAC cohort - 05/11/2008
B number:
B732
Principal applicant name:
Dr Beate St. Pourcain (University of Bristol, UK)
Co-applicants:
Dr Dave Evans (University of Bristol, UK), Dr Nic Timpson (University of Bristol, UK), Prof George Davey Smith (University of Bristol, UK)
Title of project:
Follow-up analysis of signals associated with early developmental traits (ALSPAC GWAS) within the complete ALSPAC cohort.
Proposal summary:
The aim of this proposal is to perform follow-up genotyping of the top associated signals associated with early developmental traits within the remaining ALSPAC sample in order to replicate findings from the original ALSPAC genome-wide analysis. The signal at each respective locus will be represented through 1-2 common SNPs identified from the original ALSPAC genomewide association testing in conjunction with bioinformatics analysis. The selected SNPs will also be subjected to further analysis in other large birth cohorts.
Date proposal received:
Wednesday, 5 November, 2008
Date proposal approved:
Wednesday, 5 November, 2008
Keywords:
Development, GWAS
Primary keyword: