B898 - Replication study A common variant on chromosome 11q13 is associated with atopic dermatitis - 26/10/2009
B number:
B898
Principal applicant name:
Dr Raquel Granell (University of Bristol, UK)
Co-applicants:
Prof John Henderson (University of Bristol, UK), Prof George Davey Smith (University of Bristol, UK)
Title of project:
Replication study: A common variant on chromosome 11q13 is associated with atopic dermatitis.
Proposal summary:
Common variant (rs7927894) has a reasonably strong effect on atopic dermatitis [1]. We propose two
analyses: 1) to look at the association of this genetic variant with atopic dermatitis in ALSPAC and 2) to look at the association of this genetic variant with asthma, given the effect of filaggrin on asthma.
References
[1] Gordillo et al. A common variant on chromosome 11q13 is associated with atopic dermatitis Nat Genet. 2009 May;41(5):596-601.
Date proposal received:
Monday, 26 October, 2009
Date proposal approved:
Monday, 26 October, 2009
Keywords:
Genetics, Skin
Primary keyword: