B1126 - Analysis of 4 SNPs associated with permanent tooth eruption in additional growth phenotypes - 08/03/2011

B number: 
B1126
Principal applicant name: 
Dr Frank Geller (Statens Serum Institut, Copenhagen, Europe)
Co-applicants: 
Dr Dave Evans (University of Bristol, UK), Dr Nic Timpson (University of Bristol, UK), Miss Ghazaleh Fatemifar (University of Bristol, UK), Prof Mads Melbye (Statens Serum Institut, Copenhagen, Europe), Dr Bjarke Feenstra (Statens Serum Institut, Copenhagen, Europe)
Title of project: 
Analysis of 4 SNPs associated with permanent tooth eruption in additional growth phenotypes.
Proposal summary: 

We performed a genome-wide association study of permanent tooth eruption and identified four associated genetic variants. ALSPAC data provide an excellent opportunity to check these 4 SNPs in other growth related phenotypes to answer the question whether the variants are involved in growth in a more general way. Therefore, we are interested in the analysis of these four SNPs in dentition related, growth and developmental phenotypes within ALSPAC. The results will after discussion with Drs Timpson and Evans be mentioned in the manuscript on permanent tooth eruption and displayed in the Supplementary Material.

Date proposal received: 
Tuesday, 8 March, 2011
Date proposal approved: 
Tuesday, 8 March, 2011
Keywords: 
Growth, Teeth
Primary keyword: