B1312 - Birth order and cardiovascular risk factors a comparison between the Pelotas cohorts and ALSPAC - 16/02/2012

B number: 
B1312
Principal applicant name: 
Dr Laura Howe (University of Bristol, UK)
Co-applicants: 
Prof George Davey Smith (Not used 0, Not used 0), Prof Debbie A Lawlor (Not used 0, Not used 0), Prof Cesa Victora (Not used 0, Not used 0), Pedro Hallal (Not used 0, Not used 0), Dr Alicia Matijasevich (Not used 0, Not used 0)
Title of project: 
Birth order and cardiovascular risk factors: a comparison between the Pelotas cohorts and ALSPAC
Proposal summary: 

Birth order and cardiovascular risk factors: a comparison between the Pelotas cohorts and the Avon Longitudinal Study of Parents and Children

Main research questions

1. Is there an association between birth order and CVD risk factors in ALSPAC? 2. Is the association between birth order and CVD risk factors consistent across the 3 Pelotas cohorts 3. What differences in the confounding structure could explain the different associations in ALSPAC and Pelotas (and potentially across the three Pelotas cohorts)

Analysis plan 1.Is there an association between birth order and CVD risk factors in ALSPAC?

2.Is the association between birth order and CVD risk factors consistent across the 3 Pelotas cohorts ?

3.What differences in the confounding structure could explain the different associations in ALSPAC and Pelotas (and potentially across the three Pelotas cohorts)

Date proposal received: 
Thursday, 16 February, 2012
Date proposal approved: 
Thursday, 16 February, 2012
Keywords: 
Birth Outcomes, Cardiovascular
Primary keyword: