B2048 - CLOSER work package one Data harmonisation of measures of biological function and structure across the cohorts - 18/07/2013

B number: 
B2048
Principal applicant name: 
Dr William Johnson (MRC Unit for Lifelong Health and Ageing, UK)
Co-applicants: 
Dr Rebecca Hardy (MRC Unit for Lifelong Health and Ageing, UK), Prof Jane Elliott (University of London, UK), Prof Diana Kuh (University College London, UK), Dr Leah Li (University College London, UK)
Title of project: 
CLOSER work package one: Data harmonisation of measures of biological function and structure across the cohorts.
Proposal summary: 

Aims:

To facilitate cross cohort work by harmonising measures of biological structure and function across the UK birth cohort studies, starting with weight and height in the 1946, 1958, 1970, 2000 birth cohort studies, plus ALSPAC. To sue the harmonised measures in two demonstration papers that:

1) compare body size distributions and mean trajectories, across different phases of the life course, between cohorts, and

2) investigate how SEP inequalities (using measures harmonised in CLOSER work package 2) in body size trajectories, across different phases of the life course, differ between cohorts. To extend the harmonised dataset to include data from other birth cohort studies (e.g. HCS, SWS, Biobank) and other measures of biological structure and function (e.g. blood pressure and grip strength), if necessary.

Date proposal received: 
Tuesday, 9 July, 2013
Date proposal approved: 
Thursday, 18 July, 2013
Keywords: 
Cross Cohort Study
Primary keyword: 
Methods