B2069 - Androgens in maternal serum during gestation and child androgen levels in autism spectrum conditions and autistic traits - 29/08/2013

B number: 
B2069
Principal applicant name: 
Prof Simon Baron-Cohen (University of Cambridge, UK)
Co-applicants: 
Dr Bonnie Auyeung (University of Cambridge, UK), Ms Alexa Pohl (University of Cambridge, UK)
Title of project: 
Androgens in maternal serum during gestation and child androgen levels in autism spectrum conditions and autistic traits.
Proposal summary: 

Aims: 1) To test if maternal free and total testosterone are elevated during pregnancy in autism spectrum conditions (ASC), and are correlated to number of autistic traits. 2) To test if maternal androgen levels mediate the reported relationship between gestational complications (i.e. hypertensive and hyperglycemic disorders of pregnancy) and autism risk. 3) To test if children with ASCs have elevated levels of androgens, and if number of autistic traits are correlated with elevated levels of androgens during childhood and adolescence.

Date proposal received: 
Monday, 19 August, 2013
Date proposal approved: 
Thursday, 29 August, 2013
Keywords: 
Endocrine, Pregnancy
Primary keyword: 
Autism