B2094 - Rare deleterious mutations psychiatric disease and intermediate behavioural phenotypes - 22/05/2014

B number: 
B2094
Principal applicant name: 
Dr Harriet Brown (University College London, UK)
Co-applicants: 
Dr James Lu (University College London, UK), Prof Karl Friston (University College London, UK), Prof Read Montague (Virginia Tech Carilion Research Institute (VTC),, USA)
Title of project: 
Rare deleterious mutations, psychiatric disease and intermediate behavioural phenotypes.
Proposal summary: 

AIMS:

1. To assess the prevelance of rare deleterious mutations (RDMs) in control cohorts (ALSPAC and TWINSUK) and in neuropsychiatric disease cohorts sequenced as part of the UK10K project.

2. To assess the phenotypic correlates of carrying such mutations.

Date proposal received: 
Friday, 18 October, 2013
Date proposal approved: 
Thursday, 22 May, 2014
Keywords: 
Mental Health
Primary keyword: 
UK10K