B2095 - Sex specific differences in the placental syndrome and markers of placentation - 24/10/2013

B number: 
B2095
Principal applicant name: 
Prof Eric Steegers (Erasmus University Medical Center, Rottterdam, the Netherlands, Europe)
Co-applicants: 
Dr Sarah Timmermans (Erasmus University Medical Center, Rottterdam, the Netherlands, Europe), Prof Debbie A Lawlor (University of Bristol, UK)
Title of project: 
Sex specific differences in the placental syndrome and markers of placentation.
Proposal summary: 

AIMS

We aim to

1) Investigate sex-specific differences in the occurrence of early onset and late onset pre-eclampsia, SGA and preterm birth

Where studies currently have relevant data and/or in the future we also plan to add to this aim with the following two aims. However, this request is currently ONLY for aim 1 above.

2) Explore sex-specific differences in markers of placentation in maternal blood

3) Undertake (epi)genetic studies assessing methylation / imprinting differences.

Date proposal received: 
Monday, 21 October, 2013
Date proposal approved: 
Thursday, 24 October, 2013
Keywords: 
Primary keyword: 
Placenta